- Transcription Factors locate promoter region (TATA box)
- TF binds with promoter
- Pol 2 begins to transcribe by reading TF
- DNA begin to unwind and become more stable
- Transcription takes place on complementary strand
Elongation:
- 5' to 3' direction
- anti-parallel from template (antisense)
- similar to coding (sense)
- T (thymine) is replaced by U (uracil)
- Goes from upstream to down stream
Termination:
- Stops when it reaches AAAAUAAA
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